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- Use 1-2 times/day (preferably in the evening), at the same time, should combine physical exfoliation 2-3 times/week, avoid strong chemical exfoliants, which can cause skin irritation

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The cells were differentiated with PC-conditioned medium and cARLA (48 h) and the confluent monolayers were incubated with nanocarriers (100 g/ml) diluted in hEC culture medium at 37 C for 24 h in a CO 2 incubator

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